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專家人才

  • 姓名: 張驍
  • 性別: 男
  • 職稱: 研究員
  • 學歷: 博士
  • 電話: 
  • 傳真: 
  • 電子郵件: zhang_xiao@gibh.ac.cn
  • 通訊地址 廣州市開源大道190號

    簡歷:

  •  

    2013 GIBH

    2010-2013 Product Development/Portfolio Manager, R&D, Biotherapeutics, Molecular Devices

    2009-2010 Senior Scientist, R&D, Drug Discovery, Leica        

    2008-2009 Non-Clinical Research Fellow , Royal Hallamshire Hospital

    2005-2008 Doctoral Research Student, PhD,  Medical School, Sheffield

    2002-2005 Bachelor's Degree, Bsci, Biochemistry, University of Sheffield

    2000-2002 A-level, Barnsley College

    研究領域:

  • Cell line engineering with instrumentation development for Biotherapeutics application in an automated manner under GMP for clinical use

    hiPSCs application development for HCS / HTS drug screening and clinical application

    Cell Signalling in Innate Immunity and Inflammation for cardiovascular application

    承擔科研項目情況:

  •  

    社會任職:

  •  

    獲獎及榮譽:

  • 2012 - Co-Investigator/Applicant , BBSRC,  (grant No. BB/J009687) industry application grant: Defining TILRR regulation of distinct IL-1RI responses using systems biology – 1,2M

    2010 - R&D Exceptional Science Award,

    代表論著:

  •  US Patent No. 11183497.4-2401 & 7-3699: in ClonePixIITM

     

    ZHANG X, MONTAGUT PINO G, SHEPHARD F, KISS-TOTH E and QWARNSTROM EE, 2012. Distinct control of MyD88-dependent and AKT-regulated responses by the IL-1R1 co-receptor, TILRR. Journal of Biological Chemistry. 287(15), 12348-52 Cover of Journal issue April 6th, 2012

     

    ZHANG, XIAO, SHEPHARD, FREYA, KIM, HONG B, PALMER, IAN R, MCHARG, SELINA, FOWLER, GREGORY J S, O'NEILL, LUKE A J, KISS-TOTH, ENDRE and QWARNSTROM, EVA E, 2010. TILRR, a novel IL-1RI co-receptor, potentiates MyD88 recruitment to control Ras-dependent amplification of NF-kappaB. The Journal of biological chemistry. 285(10), 7222-32

     

    Monica Neilan, Xiao Zhang, Sheila Francis, Eva E Qwarnstrom, 2010. BAS/BSCR51 Control of vascular cell inflammatory responses through TILRR, an interleukin 1 co-receptor. Heart. 10; 96(17):e27.  

     

    M Neilan, X Zhang, T Steiner, J Boyle, S Francis, D Haskard, E Qwarnstrom, 2012. TILRR Functional Mutants Selectively Inhibit Inflammatory and Anti-Apoptotic Responses. Heart. 12; 98(10):e6

     

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